Núm 39 Febrero 2015. POLIBOTANICA 35:91-101, |
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ANTIBACTERIAL ACTIVITY OF SOME MEDICINAL EUPATORIUM SPECIES
AGAINST ANTIBIOTIC RESISTANT PATHOGENIC BACTERIA
Edgar García-Sánchez, César B. Ramírez-López, Rosa E. Martínez-Muñoz,
Alberto Flores-García, Rosa E. del Río, y Mauro M. Martínez-Pacheco
Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás
de Hidalgo, Ed. B-3, Ciudad Universitaria, Morelia, Michoacán 58030, Mexico.
Correo electrónico: mpacheco@umich.mx
Abstract
Thirty six samples arising from hexane,
dichloromethane, and methanol extracts
from four medicinal Eupatorium species
were screened against Gram positive and
Gram negative resistant bacteria associated
with nosocomial infections by disk diffusion
method. The best antibacterial extracts
were selected by correspondence analysis.
The hexane extracts showed high inhibition
against clinical isolated bacteria. The qualitative
chemical analysis was realized in
the best antibacterial hexane extracts. The
main components identified were triterpenes
and benzopyran compounds which
of extensively had been reported their
antibacterial activities. Our results showing
that medicinal Eupatorium species studied
in this work have metabolites secondary
antibacterial particularly against antibiotic
resistant strains, Klebsiella pneumoniae
and Staphylococcus aureus and validate
their uses in traditional medicine
Palabras clave: Eupatorium, antibacterial, secondary
metabolites, K. pneumoniae, S. aureus.